Gi Tae Kim1, Jae Woong Sull2

1Department of Senior Healthcare, General Graduate School, Eulji University, Seongnam, Korea 2Department of Biomedical Laboratory Science, College of Health Science, Eulji University, Seongnam, Korea


Background: Forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), and the ratio of FEV1 to FVC (FEV1/FVC) are considered as the major spirometry parameters. Serum uric acid is associated with increased risk of gout and cardiovascular disease. We analyzed the relationship between pulmonary func- tion and serum uric acid level in the Korean men and women.
Methods: This study was based on the data collected during the 2016 Korea National Health and Nutrition Examination Survey (KNHANES VII-1). A total of 3,411 adults were retrieved from KNHANES VII-1. Among 3,411 adults, 1,500 were men and 1,911 were women.
Results: In this study, a significant negative correlation was observed between serum uric acid level and pulmo- nary function values only in females. Also, in the male non- smoker group, pulmonary function values were neg- atively associated with serum uric acid level (FVC %predicted, β=-0.014; FEV1 %predicted, β=-0.015).
Conclusions: In this study, hyperuricemia was associated with the low lung function in males and females. In or- der to obtain an accurate assessment of the association between hyperuricemia and pulmonary function val- ues, further prospective cohort study in the future is necessary.
Korean J Health Promot 2019;19(4):196-201

Keywords: Uric acid, Lung diseases, Hyperuricemia, Vital capacity, Forced expiratory volume