배상근1, 전혜지2, 양현수2, 김보경2, 박기수2,3

1경북대학교 의학전문대학원 예방의학교실, 2경상대학교 의학전문대학원 예방의학교실 및 건강과학연구원, 3경상대학교병원 권역심뇌혈관질환센터

Background: Medication adherence is important for hypertension management but still stay low level. It is reasonable
method to classify medication nonadherence into intentional nonadherence and unintentional nonadherence
and manage it according to this categories. This study aimed to explore medication adherence and
its predictors in community patients with hypertension, especially dividing into intentional nonadherence and
unintentional nonadherence.
Methods: Study subjects included 1,988 patients who were prescribed hypertension drugs among 2012 community
health survey subjects of 10 cities in Gyeongsangnamdo and we analyzed medication adherence with
hypertension and its predictors. We conducted chi-square test for nominal variable and ANOVA test for continuous
variable and use multinominal regression to analyze independent predictors of intentional nonadherence
and unintentional nonadherence in contrast to medication adherence.
Results: Of the 1,988 patients, 49.7% were adherent, 26.1% were unintentionally nonadherent and 24.2% intentionally
nonadherent. Independent predictors of unintentional nonadherence were depressive symptoms
(odds ratio [OR]=1.696, P=0.047) and arthritis (OR=1.319, P=0.030) and independent predictors of intentional
nonadherence were cardiocerebrovascular disease (OR=1.464, P=0.044), self-efficacy (OR=0.984, P=0.007),
beliefs about medications questionnaire (necessity [OR=0.834, P<0.001] and concern [OR=1.236, P<0.001]).
Conclusions: In order to manage hypertension in community, improvement in medication adherence is needed.
Depressive symptom and self-efficacy need to be managed, but especially patients’beliefs about their medication
need to be considered to improve intentional nonadherence.
Korean J Health Promot 2015;15(3):121-128
Keywords: Medication adherence, Hypertension, Intention