김어진1, 김종성2, 어원철1, 최수영3, 이선경1, 정복선4

1가톨릭대학교 의과대학 대전성모병원 종합건강증진센터, 2충남대학교 의과대학 충남대학교병원 가정의학과, 3충남대학교 의과대학 가정의학과교실, 4대전보훈병원 가정의학과

Background: This study aimed to determine the correlation between blood uric acid and homocysteine levels,
based on alcohol-related facial flushing.
Methods: Among male adults who visited a health examination center of a university hospital located in
Daejeon, Korea, for a personal health examination from March 2013 to February 2014, 702 subjects were analyzed
including 401 subjects without alcohol-related facial flushing and 301 with facial flushing. Pearson’s correlation
and stepwise multivariate linear regression analyses were performed between the log homocysteine
levels and other variables including uric acid.
Results: Uric acid showed a significant positive correlation with log homocysteine (γ=0.166, P=0.001) (ß=0.176;
P=0.001) in the non-flushing group. In contrast, none of the variables showed any significant correlations with
log homocysteine in the flushing group.
Conclusions: Alcohol users not exhibiting alcohol-related facial flushing showed a positive correlation between
uric acid and homocysteine levels, whereas those without facial flushing showed no such correlation.
Korean J Health Promot 2015;15(3):91-97
Keywords: Homocysteine, Uric acid, Flushing, Alcohol drinking