정재현1,조정호1, 강익원2, 신말연1, 최혜진1, 이지현1, 김선민1

숙명여자대학교1, 홍익대학교2

Background: The purpose of this study was to determine the associations between blood lipids and blood composition with inflammatory markers in obese female college students.
Methods: Sixty obese college females (mean age: 21.06±1.81 yr, percent body fat: 32.63±3.66%) participated
in this study. We measured the following blood parameters using an enzymatic method: total cholesterol (TC),
high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglyceride (TG),
C-reactive protein (CRP), red blood cells (RBC), white blood cells (WBC), hemoglobin (Hb), and tumor necrosis
factor-α(TNF-α). Percent body fat, fat mass, weight, height, and body mass index were analyzed using
bio-electrical impedance (Biospace Co.). Pearson product-moment correlation and multiple linear regression
were used to examine correlations between TNF-αand blood parameters
Results: TNF-αwas significantly associated with HDL-C (r=-0.39, P<0.001) and Hb (r=-0.32, P=0.01). In the
multiple linear regression analysis, HDL-C (t=-2.89), RBC (t=4.41), and Hb (t=-4.08) were significant predictors
of TNF-α. HDL-C, RBC, and Hb accounted for variances in TNF-αin 41% of our obese female college subjects.
Conclusions: To properly control the level of TNF-α in obese female college students, one of the effective
strategy is to reduce HDL-C, RBC, and Hb.
Korean J Health Promot 2010;10(1):10-15

Key Words: Obese female college students, Blood lipids, Blood composition, Inflammatory markers